Poe

In Ocarina of Time and Majora's Mask
In Ocarina of Time and Majora's Mask, they can easily be defeated by slashing it with the sword. After that, you can catch their spirit in a bottle. Drinking it will usually make you recover health, but it can actually damage you as well. They can be found in Kakariko Graveyard in Oot and Stone Tower Temple in MM. Note that they'll become invisible for a while when targeting them, so you'll have to refrain from doing that.

In The Wind Waker
In TWW, you must first shine light on them with the Mirror Shield, and only then can they be harmed. They will then run around the room frantically. Occasionally, they'll possess you, causing the controls to reverse. They appear in the Earth Temple.

Notable Poes

 * Poe Sisters
 * Big Poe
 * Jalhalla, Protector of the Seal

Twilight Princess
In Twilight Princess, poes are the most important enemy. There are 2 types of poes on the game. There's the Imp Poe and the regular poe, who is entirely cloaked, and you can't see their face, and are incredibly tall.