Skulltula

These huge spiders hang from the ceiling and surprise you by dropping down and attacking you. If you go near them, they will spin around, causing you to fly away whilst getting hurt. To kill them, wait until they turn around to bear their soft belly, then attack with your sword.

In Twilight Princess, they block every one of your attacks until they are stunned with a shield attack, or when they attack, you jump aside and slash them. Or, you can defeat them by first stunning them with a Spin Attack, and then finishing them off with the Ending Blow.